Non-Hodgkin Lymphoma

Last Updated: July 3, 2026

Key Points

Cancer of white blood cells (lymphocytes)
Affects the body's immune system
Many different types exist
Treatment depends on type and stage

Overview

Non-Hodgkin lymphoma is a type of cancer that begins in white blood cells called lymphocytes. These cells are crucial for fighting infections as part of your immune system. When affected, these cells grow abnormally, forming tumors in the lymphatic system, which includes lymph nodes, spleen, and bone marrow. The exact cause is often unknown, but it involves changes in the DNA of lymphocytes. It is not contagious. Risk factors can include weakened immune systems, certain infections, and exposure to some chemicals. Treatment varies widely depending on the specific type of lymphoma, its stage, and the patient's overall health. Common approaches include chemotherapy, radiation therapy, immunotherapy, and sometimes stem cell transplants. Early diagnosis is key for effective management.

Signs and Symptoms

Swollen lymph nodes (painless)
Fever
Night sweats
Unexplained weight loss
Fatigue
Itchy skin
Abdominal pain or swelling

Things That Increase the Risk

Weakened immune system
Certain viral infections (e.g., Epstein-Barr, HIV)
Exposure to some chemicals
Older age
Family history of lymphoma

Diagnosis

Physical exam
Blood tests
Biopsy of affected tissue (e.g., lymph node)
Bone marrow biopsy
Imaging scans (CT, PET)

Treatment & Management

Chemotherapy
Radiation therapy
Immunotherapy
Targeted therapy
Stem cell transplant
Watchful waiting (for slow-growing types)

Prevention

Maintain a healthy immune system
Avoid known chemical exposures
Manage underlying infections
Regular medical check-ups
Early detection through symptom awareness

Available Treatments

Explore our range of treatment options for Non-Hodgkin Lymphoma: